International Journal of Diabetes Research
p-ISSN: 2163-1638 e-ISSN: 2163-1646
2017; 6(3): 63-67
doi:10.5923/j.diabetes.20170603.03
Karki Prabin Kumar1, Maharjan Niroj2, Shrestha Saroj3, Silwal Sanzee4
1Department of Physiology, Kathmandu Medical College and Teaching Hospital, Kathmandu, Nepal
2Department of Physiology, KIST Medical College, Lalitpur, Nepal
3Gorakh Medical & Diagnostic Center Pvt. Ltd., Bhaktapur, Nepal
4Balkot Dental Clinic, Bhaktapur, Nepal
Correspondence to: Karki Prabin Kumar, Department of Physiology, Kathmandu Medical College and Teaching Hospital, Kathmandu, Nepal.
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This work is licensed under the Creative Commons Attribution International License (CC BY).
http://creativecommons.org/licenses/by/4.0/
Background and objective: The increasing trend in prevalence of diabetes mellitus around the world is alarming. Glucose levels in diabetic patients should be regularly monitored to minimize the diabetic complications. The purpose of the present study was to study the correlation between salivary and blood glucose levels. Awareness and knowledge about diabetes and perception on blood glucose maintenance among study population was also assessed. If a close correlation were to exist, diabetic control could be monitoed by the noninvasive method of measuring salivary glucose. Methods: Age matched 50 diabetic and 50 healthy non-diabetic individuals were included in the study. Structured questionnaire was used to know the educational status and knowledge about diabetes mellitus. Estimation of serum and salivary glucose levels in fasting state were carried out by Glucose Oxidase Peroxidase (GOD-POD) method, using semi-automated machine. Results: Higher percentage of diabetic patients had good knowledge and perception about diabetes and blood glucose maintenance than healthy subjects. Among diabetics mean salivary glucose level was 9.98±3.01 mg/dl. This was much higher as compared to non-diabetic individuals (7.56±1.37 mg/dl). Mean salivary glucose levels were found to be significantly correlated with mean blood glucose levels of diabetics (r= 0.811) and non diabetics (r= 0.506). Conclusion: This study suggested that saliva may become an alternative to blood for lab diagnostic procedures if further extensive studies are done in future.
Keywords: Diabetes mellitus, Salivary glucose, Non-invasive
Cite this paper: Karki Prabin Kumar, Maharjan Niroj, Shrestha Saroj, Silwal Sanzee, A Comparative Study of Glucose Levels in Blood and Saliva of Type 2 Diabetic Patients of Balkot, International Journal of Diabetes Research, Vol. 6 No. 3, 2017, pp. 63-67. doi: 10.5923/j.diabetes.20170603.03.
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![]() | Graph 1. Correlation between blood glucose and salivary glucose in diabetics |
![]() | Graph 2. Correlation between blood glucose and salivary glucose in healthy subjects |