American Journal of Biochemistry

p-ISSN: 2163-3010    e-ISSN: 2163-3029

2024;  14(1): 5-7

doi:10.5923/j.ajb.20241401.02

Received: Jul. 22, 2024; Accepted: Aug. 15, 2024; Published: Aug. 17, 2024

 

The Electro-gravitational Chemistry and Signalling Pathways

Ratan Kumar Sarkar

India

Correspondence to: Ratan Kumar Sarkar, India.

Email:

Copyright © 2024 The Author(s). Published by Scientific & Academic Publishing.

This work is licensed under the Creative Commons Attribution International License (CC BY).
http://creativecommons.org/licenses/by/4.0/

Abstract

The mechanism of biochemistry evolved in earth-moon space-time structure. Phosphorylation is an implementation of highly suppressed reverse values(79.98) in the system to activate electro-gravitational structure that expressing cell signalling pathways. The signalling values would be electro-gravitational impulses working for biological processes.

Keywords: Phosphate Group, Cholesterol, Triglyceride, Mutation, t-RNA

Cite this paper: Ratan Kumar Sarkar, The Electro-gravitational Chemistry and Signalling Pathways, American Journal of Biochemistry, Vol. 14 No. 1, 2024, pp. 5-7. doi: 10.5923/j.ajb.20241401.02.

1. Introduction

The lunar time (184) is an indomitable dynamic quantity that can’t be stopped and if blocked activation of the system initiates. The lunar time and lunar gravity meets together i.e. 184 + 705 = 889 and 705 – 184 = 521. Correspondingly 193 +507 (reverse of lunar gravity) = 700 and 507 – 193 = 314 in the structure. The values ‘100’ is significant to block the time structurally and therefore activation of the system where 889 + 100 = 989 = 700 + 289 and where 994 (tyr ht under suppression) – 705 = 289, a point of synchronising where 195 + 94 = 289 since 900 – 705 = 195 [1].
Conversely 521 + 100 = 621 = 900 – 279 is liable to cancer development shown later. Again, 314 + 289 = 603 = 524 + 79 and 425 + 97 = 522 activates the system where 425 + 524 = 949, would be a point where the system activation is switched off.
The values 989, 969(51), 949 are all blocked by ‘9’ in both sides denoting blocking of system towards signalling pathways or switched off.
The reverse reaction is an instinct to biophysical structure where 79*10 + 153 = 943(97) where 943 – 349 = 594 = 777(183) – 183 in the structure. It is to be noted that the molecular weight of sulphuric acid is 98.079 g/mol. Phosphorylation of ser, thr or tyr is an implementation of reverse reaction (79.98) in context of electro-gravitational structure.
The molecular weight of phosphate group (PO43-) is 94.9714 g/mol that possess an electro-gravitational structure.
Here, 0.9714 or 714 (suppressed) = 519 + 195 = 425 + 289 where 519 – 195 = 324 or 2124, a highly suppressed point of synchronising of methionine (149.2124) in terms of lunar gravity and 425 – 289 = 136 in tyr-val electro-gravitational structure.
It is seen 324 = 188 + 136 where the values’188’ transits and bisected and where 188 = 94*2 and 460 = 230*2 where 230 – 94 = 136 and 230 + 94 = 324 in the structure shows a bisectional mechanism. Again, 900 – 714 = 186 = 416 – 230 where 149 + 230 = 379 and 886(94)/2 = 443 = 289 + 154 in the structure.
The matter of opposite is deviated in the system like 154 – 114 = 40 = 21 + 19 where 154 – 21 = 133(7) = 114 + 19 = 21*10 -77 and where 222 – 12 = 210 and 135 – 21 = 114 makes the system somewhat complicated.
Decimals have been avoided and difference of ‘1’ found due to change of direction not mentioned somewhere.

2. Discussions

The Tyr-Val electro-gravitational intrinsic structure:
According to lunar gravity, the tyr (181.1894) and val (117.1469) factors are segregated like 289 = 229 + 60 and 136 = 103 + 33 gives a formulation, X*2 + 100 in the biophysical structure where 289*2 + 100 = 558 = 739 (i.e. 181*0.0019 = 0.3439 or 739) – 181 and 103*2 + 100 = 306 = 423 (i.e. 117*0.0019 = 0.2223 or 423) – 117, the internal vertical values of tyr and val while 60 and 33 are associated with 195. It is seen 705 – 195 = 510 while 229 – 60 = 169 and 169*0.0019 = 0.3211 or 511 (under suppression) with a difference of 1.
The values 989 = 700 + 289 = 889 +100 where lunar time is structurally blocked and according to formula X*2 + 100, 989 + 1 = 990 = 445*2 + 100 and 900 – 445 = 455 where 455*2 + 100 = 1010 or 110, a difference of 10 found while 193 – 183 = 10 in the system.
Now, 229*2 + 100 = 558 where 558 – 113 (factor of opposite) = 445 and 558 + 113 = 671 = 900 – 229 and 60*2 + 100 = 220 = 900 – 680 where 680 = 601(79) &79 i.e. mixing of vertical and horizontal time in the structure. It is seen 558 + 220 = 778(183) and 558 – 220 = 338 = 225 + 113.
Here, 558 – 103 = 455 and 558 + 455 = 1013 or 113 and also 900 – 33*2 + 100 = 734 = 621 + 113 or 734 – 455 = 279 values found in relation to cancer due to blocking of lunar time. Again, 455 = 522 – 67 (values beyond 900 in 967 or 193) and 126(T) + 67 = 193 and 455 – 126 = 329 values found in cancer development.
It is seen 900 – 306 = 594 = 777 – 183 where 594 – 113 = 481 values found in cancer development and 558 – 306 = 252 (TT) that rotational form of 225 where 252 – 225 = 27 in electro-gravitational structure. Valine is related to methionine where 455 – 306 = 149 and 707 (core values of met) – 455 = 252.
It is also seen 220 – 94(beyond 900) = 126 (reverse of 621), 220 + 94 = 314 and correspondingly 900 – 569 (i.e. 0.1469) = 331(reverse of 133) in the structure.
There are so many relations would be cascade of signalling pathways in electro-gravitational structure.
Cancer electro-gravitational cycle:
According to G1849T V617F and G469T V157F mutations, the mutational values are 151 – 126 = 25 or 0.0475 or 475 and 0.0754 (val core values) – 0.1235 (phe core values) = -0.0481where 754 – 475 = 279 and 754 + 475 = 1229 or 329 and also 279 + 329 = 608, oxy-time needed for cell cycle [2].
It is seen 900 – 475 = 425 where 705 – 425 = 280 = 279 + 1 and 1179 – 754 = 279 and also 1179 – 329 = 850 = 425*2 would constitutes an electro-gravitational structure for cancer proliferation.
There are multi-facets core values-lunar gravity (705) – electromagnetic (425) cycle for proliferation where 425 + 279 = 704 = 705 - 1 and 754 – 425 = 329 and 754 – 705 = 49 = 474 – 425. Arising out tyr-ser chemistry a difference of 3 or 0.0057 or 57 found in the system while 326 + 3 = 329 and 481 – 57 = 424 = 425 -1.
The mutations C844T R282W shows 111 – 126 = -15 or -0.285 or -285 and 0.1289 – 0.1615 = - 0.0326 or -326 where 389 + 285 = 674 i.e. reverse of 475 with difference of 100 and 900 – 674 = 226 = 326 - 100 and also 705 – 326 = 379 = 279 +100 in the structure. It is seen 326 + 49 = 375 = 844 – 469 where 754 – 375 = 379 would shows a cyclic process.
The BRAF V600E mutation shows mutational values 754 – 1494 = -740 = -739 (rotational form of 379) - 1 where 754 = 600 + 154, a relation between molecular point and core values while 279 +3 = 282 and 154 + 3 = 157. It is seen 900 – 600 = 300 = 579 – 279 where 579 = 425 + 154 and 579 – 195 = 384 in the structure.
Phosphorylation and protein kinases:
The phosphorylation is an implementation of reverse values (79.98) in electro-gravitational structure causing activation and following signalling pathways towards biological processes.
The molecular weight of phosphoserine (C3H8NO6P) is 185.07 g/mol where 105.0930 (serine) + 79.98 = 185.07 and phosphotyrosine (C9H12NO6P) = 181.1894 + 79.98 = 261.17. The molecular difference of ser-thr, 119.1197 – 105.0930 = 14.0267.
It would be 79.97 and difference of 1 is due to the opposite direction where 98 – 79 = 19(1). It is seen the decimal part is aligned to arginine (174.2017) pre-transitional values since 97*0.0019 = 0.1843 = 0.2017 – 0.0174. The serine vertical values 105 + 79 = 183 and 97*2 = 194 is bisected where 439 + 79 = 518 = 943 – 425 (i.e. 938 – 513 = 425) and 943 – 705 = 238 = 195 + 43, a suppressed synchronised position shows implementation of highly suppressed values into the system.
The values ‘79’ = 193 – 114 (suppressed) where 489*2 = 978 (beyond 900) while 183 is a complementary values of 489 with a difference of 1 gives 183*2 = 366 = 601(79) – 235 where 235 + 114 = 349(reverse of 943) and where 967(193) – 601 = 366 in the structure.
Conversely, 97*0.0019 = 0.1843 or 943 (suppressed) and 43*0.0019 = 0.0817 or 817 = 663 (reverse of 366) + 154 where 900 – 663 = 237 = 663 – 426 causing an electro-gravitational chemistry.
It is a highly suppressed arena gives off expressions of signalling pathways.
The significance of some important values:
In electro-gravitational structure, the reverse action of electromagnetics i.e. 425 + 524 = 949 that blocked by ‘9’ in both sides switch off the activation of system and 524 – 425 = 99 or 100 in opposite direction and where 524 = 361 + 163 reverse action.
According to t-RNA factor, 66 (distance of constancy) = 51 + 15 where 51*0.0019 = 0.0969 or 969 that blocked by ‘9’ in both sides where 15*0.0019 = 0.0285 = 285 and where 285 + 69 = 354(66) in the system. In synthesis of proline (115.1311), 184 = 115 + 69 where 69(or 0.1311) breaks into horizontal time(ht) significantly would due to lunar time-lunar gravity chemistry where 900 – 411 = 489, a complementary form of lunar time (184) where 705 – 489 = 216 causes an structural adjustment of ‘16’ towards synthesis of hydroxyproline (131.13).
The activation of system starts when lunar time (184) is blocked by ‘9’ in both sides while the complementary form of 184 i.e. 489 is blocked by ‘9’ in one side.
The lunar time (184) and lunar gravity (0.1605 or 705) meets together in curvature of space-time where 989 – 100 = 184 + 705 = 889, obviously ‘100’ is an essential factor to block the lunar time and it happens in the biological structure. The values ‘989’ includes ‘12’ while 183 + 12 = 195 = 900 – 705 in the structure and 174 = 171(9) + 3 = 12 in suppressed form incorporated into 989 = 700 + 289.
Conversely 705 – 184 = 521 = 621 – 100 blocks lunar time while 279 + 621 = 900 activates for cancer development.
The values 79.98 can be derived from 184-193 chemistry while 700 – 621 = 79 and 193 + 507 = 700 and 79 + 114 (factor of opposite) = 193. Conversely 193 – 184 = 9 = 98- 89 that mathematically symmetrical with 601(79) + 20 = 621 while 79* 0.0019 = 0.1501 or 601 and conversely 184 – 106 = 78 = 79 – 1.
It is seen 949 – 489 = 460 (expansion values) and 969 – 489 = 480 (or 1380) in the structure while 705 + 69 = 774 and 705 + 49 = 754 (core values of val).
It is seen 0.0601(79) – 0.0079 = 0.0522 or 522 and 184 – 79 = 105 = 106 – 1 and also 601 + 79 = 680 = 888 – 208 where 522 – 208 = 314 = 507 – 193 in the structure.
Cholesterol(C27H46O) and Triglyceride(C6H8O6):
The molecular weight of two interface biochemical compounds cholesterol and triglyceride are 386.213 and 176.300 respectively after suppression of horizontal time.
It is significant that the vertical and decimal values can be directly added with favourable values where 386 + 213 = 599 where 900 – 599 = 301 = 300 + 1 that comply with triglyceride ht values.
In reverse system, the positive and negative values of triglyceride are 300 + 176 = 476 and 300 – 176 = 124 where 476 + 124 = 600(79, bisected) and 79 + 97 = 176 and also 386 + 213 = 599 = 600 -1.
Here, 777(183) – 176 = 601(79) where 900 – 777 = 123 = 300 – 176 with a difference of 1.

3. Conclusions

The lunar time (184) is an unstoppable dynamic quantity activates the system while 989 blocked by ‘9’ in both sides, a structural blocking of lunar time. The values 949 and 969(51) while attains would switched off the activation of the system. The formula X*2 + 100 here clarifies the structural transactions to some extent. The activation of electro-gravitational circuit would be needed towards influx of electro-gravitational impulses with varied values for cell signalling pathways. Phosphorylation is an implementation of reverse values (79.98) activates electro-gravitational structure. Reverse reaction is an inherent characteristic of biophysical structure. There is a multi-facets core values-lunar gravity- electromagnetic and even molecular point processes for development of cancer. The interface biochemical compound macromolecular assemblies would be the results of electro-gravitational chemistry in earth-moon space-time structure.

References

[1]  American Journal of Chemistry, 2024 14(1): 1-3.
[2]  American Journal of Chemistry, 2024 14(3): 35-36.